- Frost & Sullivan 2016 APAC Pain Relief Technologies Innovation Award
- Singapore Enterprise Association - Medal of honour Award- Top 1000 Elite & Trustworthy SMEs
- Unity Popular Choice Award
- Guardian Health&Beauty Award
- Woman Body Award Livewell
Peer-Reviewed:
URAH Shown to Increase Cartilage Thickness by 61% in Just 12 Weeks in Osteoarthritis Patients
UK Research Publication:
URAH delivers up to 10x more absorption compared to pills.
Clinically Proven. Third-Party Tested
Clinical Research on Arthritis Patients
URAH Micellar Vs Others
URAH Micellar Vs Others
| Feature | URAH Micellar | Typical Pills | Typical Injections |
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Proven to increase joint cartilage thickness to avoid bone-bone grinding for long-lasting relief, flexibility and mobility
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Recommended in Hospitals and Clinics
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Some are strongly recommended against by the American College of Rheumatology | ||
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Track record of safety and effectiveness
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25 Yrs | Results vary | |
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Clinically proven
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Results vary | Results vary | |
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Breakthrough Delivery Technology (10x more absorption)
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Rapid Localized Relief
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Results vary |
GET STARTED TODAY
For Daily Joint Support
Joint health Omega-3
8% Active Micellar Glucosamine + Omega-3
─ Suitable For Ages 18 and Above
─ Fast-acting, targeted relief for the whole body
─ Enhanced boost in collagen + hyaluronic acid production for skin, hair & nails
─ Long lasting effects on flexibility and mobility for all joints and cartilage
─ Effective supplementation without the side effects of pills and invasive treatment
─ Non-GMO & Natural
For Active Lifestyles
Sporting Cream MSM
8% Active Micellar Glucosamine + Omega-3 + MSM
─ Suitable For Ages 18 and Above
─ Fastest-acting (as soon as 30mins), targeted relief for whole body for post-workout recovery
─ Enhanced boost in collagen + hyaluronic acid production for skin, hair & nails
─ Long lasting effects on flexibility and mobility for all joints and cartilage
─ Effective supplementation without the side effects of pills and invasive treatment
─ Non-GMO & Natural
For Joint + Bone Health (Extra Strength)
Bone health Bio-Calcium
10% Active Micellar Glucosamine + Omega-3 + Bio-Calcium
─ Suitable For Ages 35 and Above
─ Enhanced boost in bone density for bone structures linked to saggy skin and wrinkle formation
─ Enhanced boost in bone density for weak bones and chronic issues
─ Fast-acting, targeted relief for whole body
─ Enhanced boost in collagen + hyaluronic acid production for skin, hair & nails
─ Long lasting effects on flexibility and mobility for all joints and cartilage
─ Effective supplementation without the side effects of pills and invasive treatment
─ Non-GMO & Natural
Let customers speak for us
URAH success stories
Hear reviews from real customers on how URAH plays a key role in their daily health journeys.
URAH Stories
FAQs
Understanding the Absorption Problem
Glucosamine pills frequently fail to deliver meaningful joint pain relief due to fundamental limitations in how your body absorbs these nutrients through the digestive system.
The Glucosamine Challenge: Low Bioavailability
Poor Absorption Rates
When you take glucosamine orally, most of the active ingredient never reaches your joints. Here's why:
- Digestive breakdown: Glucosamine is extensively metabolized by stomach acid and liver enzymes before entering your bloodstream
- Limited bioavailability: Only a small percentage of the ingested dose is absorbed in a form your joints can use
- Distribution challenges: Even the glucosamine that enters your bloodstream is distributed throughout your entire body, with minimal amounts reaching targeted joint tissues
What the Research Shows
Multiple systematic reviews and meta-analyses published in medical journals, including the Annals of Internal Medicine and BMJ, have found that oral glucosamine provides little to no clinically significant benefit for osteoarthritis symptoms compared to placebo.
Gastrointestinal Side Effects
Glucosamine compounds are naturally acidic. Standard therapeutic doses (typically 1,500–2,000 mg daily) can cause:
- Nausea and stomach discomfort
- Constipation or diarrhea
- Heartburn and gastric irritation
- In some cases, gastric ulcers
These symptoms are often mistakenly attributed to "glucosamine allergy" when they're actually caused by the compound's acidic nature and high oral dosage requirements.
The bottom line: Oral glucosamine faces a triple challenge—poor absorption, systemic distribution that bypasses joints, and gastrointestinal tolerability issues.
References
- BMJ. 2013; Office of Dietary Supplements, NIH (Long-term calcium intake and mortality)
- Various systematic reviews on oral glucosamine efficacy published in Annals of Internal Medicine, BMJ, and Cochrane Database
While some foods contain glucosamine (shellfish shells, animal cartilage, bone broth), obtaining therapeutic amounts from diet alone is insufficient. Here's why:
Limited sources—few foods contain meaningful amounts of glucosamine.
95% loss through biological processes—when glucosamine is consumed orally, up to 95% is destroyed through digestion, liver metabolism, and other biological processes before reaching joints. This means dietary or oral glucosamine rarely delivers enough to create major improvements.
Safe, superior delivery—URAH's micellar technology bypasses these losses entirely, delivering glucosamine through your skin 10x more effectively than oral supplements, without gastrointestinal side effects.
The effectiveness comparison is complex and depends heavily on delivery method. Research shows mixed results when comparing oral forms, but delivery method makes the critical difference.
Peer-Reviewed Clinical Evidence on Oral Collagen vs. Oral Glucosamine: A randomized, double-blind clinical trial found that UC-II collagen treatment decreased VAS pain scores by 40% after 90 days compared to 15.4% in the glucosamine plus chondroitin group (1, 2). A subsequent multicenter study with 191 participants confirmed these findings, showing UC-II significantly reduced overall WOMAC scores compared to both placebo and glucosamine-chondroitin combinations over 180 days (3).
The Bioavailability Challenge: Both oral collagen and oral glucosamine face significant absorption limitations. Peer-reviewed research demonstrated that oral collagen has an absolute bioavailability of approximately 49.6% and relative bioavailability of 57.8% (4, 5), meaning nearly half is lost before reaching target tissues. Studies show that collagen-derived Hyp-peptides increase to maximum blood levels at 1 hour after ingestion and revert to initial levels within 24 hours (6), indicating rapid metabolism limits sustained effectiveness. Meanwhile, oral glucosamine suffers from up to 95% loss through digestive processes, liver metabolism, and biological barriers before reaching joints.
Safety of Delivery Technology: Oral glucosamine can cause gastrointestinal side effects like nausea, heartburn, and diarrhea, and may interact with blood-thinning medications. Oral collagen supplements face similar digestive challenges and rapid metabolism. URAH's topical micellar technology bypasses these issues entirely—Urah's gentle, clinically-tested delivery system absorbs through the skin without digestive side effects, medication interactions, or the rapid metabolism that limits oral collagen's effectiveness.
Why Topical Delivery Changes Everything: URAH Micellar Creams fundamentally solve the bioavailability problem that limits both oral collagen and oral glucosamine. URAH's clinically-tested micellar delivery technology bypasses the digestive system entirely, delivering active ingredients directly through the skin to joint tissues 10x more effectively than oral supplements.
Clinical Results Matter: While oral UC-II collagen showed advantages over oral glucosamine in clinical trials, URAH's approach delivers superior results to both. An Peer reviewed study demonstrated a 61% increase in cartilage thickness in just 12 weeks—results that are difficult or impossible to achieve with oral supplementation of either ingredient due to bioavailability and metabolism limitations.
The Bottom Line: The question isn't whether collagen or glucosamine is "better"—it's about how effectively your body can use them and how long they remain active. With oral supplements, you face significant losses through digestion, rapid metabolism (collagen peptides return to baseline within 24 hours), and unclear targeting. URAH's topical delivery ensures active ingredients reach joint tissues directly, efficiently, and remain functional longer, making the comparison with oral supplements fundamentally different. Topical application with advanced micellar technology provides a scientifically superior approach to joint health that neither oral collagen nor oral glucosamine can match.
References:
- Crowley DC, Lau FC, Sharma P, et al. Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial. Int J Med Sci. 2009;6(6):312-321.
- Crowley DC, Lau FC, Sharma P, et al. Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial. Int J Med Sci. 2009;6(6):312-321.
- Lugo JP, Saiyed ZM, Lau FC, et al. Undenatured type II collagen (UC-II®) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteers. J Int Soc Sports Nutr. 2013;10(1):48. / Lugo JP, Saiyed ZM, Lane NE. Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study. Nutr J. 2016;15:14.
- Iwai K, Hasegawa T, Taguchi Y, et al. Identification of food-derived collagen peptides in human blood after oral ingestion of gelatin hydrolysates. J Agric Food Chem. 2005;53(16):6531-6536.
- Iwai K, Hasegawa T, Taguchi Y, et al. Identification of food-derived collagen peptides in human blood after oral ingestion of gelatin hydrolysates. J Agric Food Chem. 2005;53(16):6531-6536.
- Ohara H, Matsumoto H, Ito K, Iwai K, Sato K. Comparison of quantity and structures of hydroxyproline-containing peptides in human blood after oral ingestion of gelatin hydrolysates from different sources. J Agric Food Chem. 2007;55(4):1532-1535.
Not always. Because glucosamine is acidic, oral supplements can cause gastric issues like nausea, ulcers, and “glucosamine allergy” symptoms such as bloating, wheezing, or constipation—especially with long-term use.
By nature, Glucosamine is an unstable chemical substance. When exposed to air it is easily degraded and denatured. In order to be used, Glucosamine has to be compounded into a stable acidic salt. E.g. Glucosamine sulphate, Glucosamine hydrochloride, acetyl glucosamine, etc. All these stable glucosamine compounds are ACIDIC
High oral dosages (which is typically 1500 to 2000mg daily) of Glucosamine is normally prescribed to make up for the high loss in the gastric system. But, because these Glucosamine compounds are acidic, high oral dosages inadvertently causes hyper acidity or Gastrointestinal toxicity. Prolonged oral administration of Glucosamine drugs and supplements may therefore lead to Gastric irritations, ulceration and other gastrointestinal complications (commonly refered to as "glucosamine allergy")
Yes, they can be. Multiple studies have linked high-dose calcium supplements to serious health risks, including:
- Kidney stones
- Arterial calcification
- Increased risk of heart attacks and stroke
These risks occur because oral calcium is often absorbed too quickly, causing calcium spikes in the blood that the body cannot properly regulate.
URAH Bio-Calcium Cream offers a safer alternative.
After years of research, URAH has developed a proprietary Transdermal Bio-Calcium cream that delivers a slow and steady supply of optimal calcium through the skin, directly to where it’s needed. Our formula also includes 10% glucosamine and essential vitamins, providing targeted support for bones, joints, and surrounding tissues without gastric or cardiovascular side effects.
No. Calcium supports bone density, not joint cartilage or soft tissues.
Joint pain usually stems from cartilage degeneration (osteoarthritis), not bone weakness (osteoporosis). Glucosamine targets cartilage and soft tissues.
Not directly.
Osteoporosis weakens bones and may lead to fractures, while osteoarthritis causes joint pain due to cartilage wear and tear. They are different conditions that require different approaches.
What Makes URAH Unique
No, glucosamine creams vary significantly in their formulation, delivery technology, and absorption rates. The key differences include:
Delivery System: Traditional topical creams may contain glucosamine, but without advanced delivery technology, the molecules often remain on the skin's surface rather than penetrating to reach joints and cartilage. URAH Micellar Creams use proprietary URAH-MD-tech with micellar technology, which has been clinically proven to deliver active ingredients 10x more effectively than standard oral supplements.
Safety of Delivery Technology: Not all delivery methods are created equal—some use harsh chemical penetration enhancers or solvents that can irritate skin or cause adverse reactions. URAH's micellar delivery technology is designed to be gentle and safe, using naturally-derived micelles that transport active ingredients through the skin barrier without damaging it. This clinically-tested delivery system allows therapeutic compounds to reach joints and tissues safely, without the gastrointestinal side effects, drug interactions, or digestive issues commonly associated with oral glucosamine supplements.
Ingredient Quality: The form of glucosamine used (glucosamine sulfate vs. glucosamine hydrochloride), concentration levels, and purity can vary widely between products. Clinical-grade formulations ensure consistency and potency.
Clinical Testing: Most topical joint products lack rigorous clinical validation. URAH Micellar Creams have undergone clinical testing demonstrating measurable results, including a 61% increase in cartilage thickness in 12 weeks for chronic joint conditions.
Absorption Rate: The critical factor isn't just what's in the cream—it's whether your body can actually use it. Standard creams may have poor bioavailability, while advanced formulations like URAH's micellar delivery system are designed to transport active ingredients through the skin barrier directly to where they're needed.
When choosing a glucosamine cream, prioritize products with safe, clinically-validated delivery technology, transparent ingredient lists, and documented results.
URAH uses MD-Tech (Micellar Delivery Technology)
MD-Tech is a proprietary transdermal delivery system developed by Urah Research Lab in Singapore formulated using a bio-surfactant technology that was Patented in the US (No. 6846916), Japan (No. 4580234), and Singapore (No. SG 102614). that delivers high concentrations of glucosamine and bio-calcium directly into joints and muscles—without side effects or greasy residue.
Not all glucosamine creams are created equal. Many offer temporary sensations without delivering real benefits. Here's how to spot a genuinely effective formula:
1. No Hot or Cooling Sensation
Avoid creams that rely on menthol, camphor, or chili extracts for a placebo effect. These may feel good temporarily but don't treat the root cause—and some can even irritate the skin.
2. Check the Glucosamine Concentration
Many brands hide low glucosamine levels. A quality cream should contain at least 7% active glucosamine or 70mg per 1g of cream. If there’s no percentage listed, be skeptical.
3. Ensure Cream Stability
Unstable creams separate into water and oil. If you’re told to “shake before use,” that’s a red flag. Press the tube—if watery spots come out or water pools at the bottom, it’s not high quality.
4. Look for True Skin Penetration
Real transdermal delivery works without leaving residue. Rub 1g on one wrist, wait 15 mins, then rub again. If white flakes or powder appear, it’s sitting on your skin—not entering your body.
5. Check Acidity (pH)
Use pH strips or a meter. A cream with pH below 2.3 is too acidic and can irritate your skin. Safe, skin-friendly creams are properly balanced.
URAH Micellar Creams are formulated with Obalin® patented technology—ensuring stable emulsions, deep skin penetration, and clinical-grade glucosamine concentrations. Always check the science behind the cream before you trust it.
1g of URAH Micellar Cream delivers bioequivalent glucosamine to 2000mg of oral pills
—but without gastric side effects. It’s also more cost-effective in the long run.
Is URAH clinically tested?
Yes. A clinical trial across 20 Singaporean clinics showed pain relief in just 4 weeks, with no gastric side effects. Results were published in the International Journal of Pharmaceutical Science (2011).
How to Use URAH Effectively
Apply approximately 0.5g per joint or targeted area, 1–2 times daily.
A single 50g tube provides around 100 applications, offering several weeks of consistent use.
No adverse effects have been reported.
The maximum recommended dose is 800mg/day, but even higher usage has shown no known risks.
When it comes to bone health and density, results naturally take longer.
Bone regeneration is a gradual biological process that can take several months typically 9-18 months depending on the type of supplementation and the state of the bones. URAH’s Bone Health Cream is formulated with active bio-calcium and glucosamine molecules designed to stimulate new bone formation and improve calcium absorption over time.
For optimal, cumulative results, we recommend applying the cream at least 1–2 times daily on targeted areas for at least 6 months.
For best results, URAH cream should be used consistently—even after symptoms improve.
Our formulas are designed not just for fast relief but for long-term support and protection of your joints, muscles, and bones.
When it comes to bone health, early prevention is key. Bone density peaks around age 25 and begins to decline with age. That’s why we recommend starting URAH Bone Health Cream as part of your daily routine:
- Women: Begin in your 30s to slow bone loss before and during menopause, when decline accelerates.
- Men: Ideal to start maintenance in your late 30s to 40s, before age-related bone weakening sets in.
Think of URAH as your daily defense—precision care today for a stronger, more mobile tomorrow.
Store below 30°C in a cool, dry place.
Once opened, use within 3 months for best results. If the seal is unbroken, the cream remains effective until the expiry date.
Performance, Prevention & Recovery
Absolutely.
Use URAH SPORTING CREAM MSM before and after workouts to reduce inflammation, support recovery, and prevent skin sagging caused by tissue stress.
Yes.
URAH’s advanced transdermal creams support skin regeneration, collagen repair, and faster wound healing—especially for active or aging users.
Absolutely. URAH supports daily joint health, tissue regeneration, and bone strength
—making it ideal for preventive care, even before symptoms appear.